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Keep an eye on Intently (2)pentobarbital will minimize the level or influence of suvorexant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Potent CYP3A4 inducers may perhaps lessen suvorexant efficacy; if improved suvorexant dose expected, never exceed twenty mg/daypentobarbital will reduce the level or impact of bup